POLY(N-ISOPROPYL ACRYLAMIDE)
POLY(N-ISOPROPYL ACRYLAMIDE)
CAS: 25189-55-3
Molecular Formula: C6H11NO
POLY(N-ISOPROPYL ACRYLAMIDE) - Names and Identifiers
| Name | POLY(N-ISOPROPYL ACRYLAMIDE) |
| Synonyms | POLY(N-ISOPROPYL ACRYLAMIDE) n-(1-methylethyl)-2-propenamidhomopolymer 2-Propenamide, N-(1-methylethyl)-, homopolymer |
| CAS | 25189-55-3 |
POLY(N-ISOPROPYL ACRYLAMIDE) - Physico-chemical Properties
| Molecular Formula | C6H11NO |
| Molar Mass | 113.15764 |
| Density | 1.386 g/cm3 |
| Melting Point | 96 °C(lit.) |
| Appearance | Morphological powder, color white to off-white |
| Storage Condition | -20°C |
| Physical and Chemical Properties | EPA Chemical Information 2-Propenamide, N-(1-methylethyl)-, homopolymer (25189-55-3) |
| Use | Uses Thermosensitive polymer can be used to form hydrogel. When the temperature is increased to about 32 ℃, the aqueous polymer can change from a soluble state to an insoluble state. |
POLY(N-ISOPROPYL ACRYLAMIDE) - Risk and Safety
| WGK Germany | 1 |
POLY(N-ISOPROPYL ACRYLAMIDE) - Introduction
POLY(N-ISOPROPYL ACRYLAMIDE), referred to as PNIPAM, is a heat-sensitive polymer material. Its nature includes the following aspects:
1. Heat sensitivity: PNIPAM shows water solubility at low temperature, while water solubility decreases and solubility becomes smaller at high temperature. This temperature sensitivity allows PNIPAM to switch between Sol and gel states over a range of temperatures.
2. Solubility: PNIPAM has good solubility in water and can form a transparent solution. At high temperature, PNIPAM solution can form a gel state by reducing the temperature.
3. Biocompatibility: PNIPAM has good biocompatibility in vivo, which means that it can be used in biomedical fields, such as drug delivery, tissue engineering and biosensors.
PNIPAM has a wide range of applications, some of which include:
1. Pharmaceutical field: PNIPAM can be used as a drug delivery system to achieve controlled release of drugs by regulating temperature. At the same time, due to its biocompatibility, it can also be used in cell culture and tissue engineering.
2. Biosensor: PNIPAM can be prepared into a thermosensitive biosensor for detecting biological molecules, bacteria or viruses.
3. Smart materials: Due to its temperature sensitivity, PNIPAM can be prepared into smart materials for applications in controlled release, nanotechnology, and microfluidic systems.
The preparation methods of PNIPAM mainly include Free Radical Polymerization and coordination polymerization. The free radical polymerization method is a polymerization reaction of N-isopropylacrylamide monomer together with an initiator and a crosslinking agent in a suitable solvent. The coordination polymerization law is the coordination reaction of metal ions with N-isopropylacrylamide monomer to form a polymer.
Regarding the safety information of PNIPAM, it is a relatively safe polymer material. However, for any chemical, proper handling and storage are very important. When using PNIPAM, it is necessary to follow relevant safety procedures, avoid direct contact with skin and eyes, and avoid inhaling its dust. When using PNIPAM, use appropriate protective measures, such as wearing gloves and goggles. At the same time, PNIPAM should be stored in a dry and cool place, avoiding contact with oxygen, water and fire. If an accident occurs, rinse immediately with water and seek medical help if necessary. Please read the Product Safety Data Sheet (MSDS) before any operation.
1. Heat sensitivity: PNIPAM shows water solubility at low temperature, while water solubility decreases and solubility becomes smaller at high temperature. This temperature sensitivity allows PNIPAM to switch between Sol and gel states over a range of temperatures.
2. Solubility: PNIPAM has good solubility in water and can form a transparent solution. At high temperature, PNIPAM solution can form a gel state by reducing the temperature.
3. Biocompatibility: PNIPAM has good biocompatibility in vivo, which means that it can be used in biomedical fields, such as drug delivery, tissue engineering and biosensors.
PNIPAM has a wide range of applications, some of which include:
1. Pharmaceutical field: PNIPAM can be used as a drug delivery system to achieve controlled release of drugs by regulating temperature. At the same time, due to its biocompatibility, it can also be used in cell culture and tissue engineering.
2. Biosensor: PNIPAM can be prepared into a thermosensitive biosensor for detecting biological molecules, bacteria or viruses.
3. Smart materials: Due to its temperature sensitivity, PNIPAM can be prepared into smart materials for applications in controlled release, nanotechnology, and microfluidic systems.
The preparation methods of PNIPAM mainly include Free Radical Polymerization and coordination polymerization. The free radical polymerization method is a polymerization reaction of N-isopropylacrylamide monomer together with an initiator and a crosslinking agent in a suitable solvent. The coordination polymerization law is the coordination reaction of metal ions with N-isopropylacrylamide monomer to form a polymer.
Regarding the safety information of PNIPAM, it is a relatively safe polymer material. However, for any chemical, proper handling and storage are very important. When using PNIPAM, it is necessary to follow relevant safety procedures, avoid direct contact with skin and eyes, and avoid inhaling its dust. When using PNIPAM, use appropriate protective measures, such as wearing gloves and goggles. At the same time, PNIPAM should be stored in a dry and cool place, avoiding contact with oxygen, water and fire. If an accident occurs, rinse immediately with water and seek medical help if necessary. Please read the Product Safety Data Sheet (MSDS) before any operation.
Last Update：2024-04-10 22:41:03
